Buprenorphine (Subutex)

Buprenorphine (Subutex) is an opiate antagonist, a relatively new drug in the fight against addiction. See a more detaield description of its use combating opiate addiction here.

Subutex falls into a class of medications called opioid partial agonists. It works by binding to the same receptors in the brain that are targeted by opioids, such as heroin or prescription painkillers. However, unlike full agonists like heroin, Subutex only stimulates these receptors partially. This means it can help manage withdrawal symptoms and cravings while reducing the likelihood of euphoria or other negative effects associated with full agonists.

One of the significant benefits of Subutex is its ability to alleviate withdrawal symptoms making it easier for individuals to stop using opioids. Withdrawal symptoms can include muscle aches, nausea, anxiety and insomnia, which can be incredibly challenging to cope with and often lead to relapse. Subutex helps to ease these symptoms, allowing you to focus on your recovery without the burden of intense physical discomfort.

Subutex is also known for its long-lasting effects. A single dose can provide relief for up to 24 to 72 hours, depending on the individual. This means fewer medication administrations, reducing the risk of missed doses or medication misuse. Additionally, Subutex is available both in pill form and in a dissolvable tablet, providing flexibility and ease of administration.

It’s important to note that Subutex should always be used under medical supervision, as it is a prescription medication. In most cases, it is provided as part of a comprehensive treatment program, including counselling and behavioural therapies. These programs aim to address the root causes of addiction and help individuals develop the necessary skills for long-term recovery.

While Subutex has proven to be effective in reducing opioid use and supporting individuals in their recovery process, it is not a solution on its own. Recovery involves various factors, including individual commitment, social support and lifestyle changes. However, Subutex can be a valuable tool in the addiction recovery process offering hope and a newfound sense of control.

What is Buprenorphine and how does it work in treating opioid addiction?

Buprenorphine, known by its commercial name Subutex, is an innovative treatment for opioid addiction, functioning as an opioid partial agonist. It attaches to opioid receptors in the brain without fully activating them, effectively reducing withdrawal symptoms and cravings without causing the euphoria associated with opioids like heroin and prescription painkillers. This mechanism is key to facilitating the transition away from opioid dependence, managing withdrawal symptoms such as muscle aches, nausea, anxiety and insomnia, which can lead to relapse if untreated.

How long does the effect of Subutex last and how does this benefit treatment?

Subutex provides sustained relief from opioid withdrawal symptoms with its effects lasting between 24 to 72 hours depending on the dosage and individual response. This extended duration of action reduces the need for frequent dosing, thereby lowering the risks of missed doses or potential misuse of the medication. This feature of Subutex is crucial in creating a more manageable and effective treatment regimen for individuals in recovery.

In what forms is Subutex available and why does this matter?

Subutex is available in both pill and dissolvable tablet forms, offering flexibility in administration methods to suit individual preferences and needs. This versatility ensures that treatment can be tailored to the patient’s lifestyle and circumstances, facilitating adherence to the medication regimen and enhancing the overall effectiveness of the treatment process.

Why is medical supervision important when using Subutex for opioid addiction treatment?

Medical supervision is critical when using Subutex for opioid addiction treatment to ensure safety and effectiveness. Subutex must be administered as part of a comprehensive treatment plan that includes counselling and behavioural therapy, addressing not just the physical aspects of addiction but also the underlying psychological and social factors. Supervision by healthcare professionals ensures the correct dosage and minimises the risk of misuse, while integrated support services provide a holistic approach to recovery.

Can Subutex alone cure opioid addiction?

Effective recovery from opioid dependence requires an approach, including personal commitment to change, social support systems and lifestyle adjustments. Subutex serves as one component of a broader strategy aimed at achieving long-term sobriety and wellness.

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    Founded in 2008, WeDoRecover has evolved from an advisory service for addiction treatment into a comprehensive provider of care, following its 2019 merger with Changes Addiction Rehab in Johannesburg. Specialising in connecting patients to top-tier addiction treatment centers in the UK, South Africa and Thailand, WeDoRecover supports individuals globally, including those from the United Arab Emirates and Europe. Accepting both South African medical aid and international health insurance our organisation facilitates access to high-quality treatment for substance and alcohol use disorders, offering individualised care that addresses the physical, mental and social needs of patients.



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    Our rehab care is a good option if you are at risk of experiencing strong withdrawal symptoms when you try stop a substance. This rehab option would also be recommended if you have experienced recurrent relapses or if you have tried a less-intensive treatment without success.

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