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Lorazepam, known by brand names such as Ativan and Temesta, is a medication belonging to the benzodiazepine class. It is primarily used for the treatment of anxiety disorders, insomnia (due to anxiety or short-term stress), and as a sedative before surgery or to treat seizures. The drug works by enhancing the effects of a specific natural chemical in the body (GABA).

One of the critical aspects of Lorazepam is its potential for addiction. It can be habit-forming, especially with long-term or excessive use, or in patients with a history of substance abuse. The risk of dependence increases with the dosage and duration of treatment and is higher in patients with a history of alcohol or drug abuse. Lorazepam works by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain. GABA helps to regulate brain activity, and by increasing its effects, lorazepam helps to calm down excessive activity in the brain, reducing anxiety and promoting relaxation.

Due to its addictive nature, discontinuing lorazepam usually requires a gradual reduction in dosage to avoid withdrawal symptoms, which can be severe. Withdrawal symptoms may include tremors, cramps, vomiting, sweating, and, in severe cases, seizures. Therefore, it is strongly advised to use lorazepam only under the strict supervision of a healthcare professional.

It was initially patented in 1963 and became available in the United States in 1977. This drug is primarily used for treating anxiety, trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting. It can be administered orally or as an injection.

The development and introduction of lorazepam, along with other benzodiazepines, can be traced back to a search for safer alternatives to barbiturates, which were widely used until the mid-20th century but had significant issues with tolerance, dependence, and overdose risk. In 1955, the first benzodiazepine, Librium, was synthesized, marking the beginning of a new era in tranquilizer medication. Diazepam, better known as Valium, was introduced in 1958 and quickly became popular. However, as the problems of dependence and withdrawal became evident with Valium, pharmaceutical companies began marketing new benzodiazepines like lorazepam as safer alternatives, though they shared many of the same risks.

Despite being marketed as different from earlier tranquilizers, lorazepam and other benzodiazepines like clonazepam and alprazolam (Xanax) have been shown to carry risks of tolerance, dependence, and challenging withdrawal symptoms. The rebranding of these drugs as “anxiolytics” in the 1970s and 1980s was an attempt to differentiate them from the increasingly notorious Valium, although their pharmacological similarities meant that they posed similar risks.

Lorazepam’s history also includes recreational use, dating back to at least the 1980s, often for its relaxant effects. There have also been reports of its misuse as a ‘date rape’ drug, although other substances are more commonly implicated in such incidents.

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    Founded in 2008, WeDoRecover has evolved from an advisory service for addiction treatment into a comprehensive provider of care, following its 2019 merger with Changes Addiction Rehab in Johannesburg. Specializing in connecting patients to top-tier addiction treatment centers in the UK, South Africa, and Thailand, WeDoRecover supports individuals globally, including those from the United Arab Emirates and Europe. Accepting both South African medical aid and international health insurance, the organization facilitates access to high-quality treatment for substance and alcohol use disorders, offering individualized care that addresses the physical, mental, and social needs of patients.

    Our team, led by Gareth Carter, offers empathetic and professional support, guiding you through every step of the treatment process. Whether you're in South Africa or abroad, our acceptance of various insurance plans makes quality care accessible, providing a platform for lasting recovery and a healthier future.

    Inpatient Rehab

    Our rehab care is a good option if you are at risk of experiencing strong withdrawal symptoms when you try stop a substance. This rehab option would also be recommended if you have experienced recurrent relapses or if you have tried a less-intensive treatment without success.


    If you're committed to your sobriety but cannot take a break from your daily duties for an inpatient program. Outpatient rehab treatment might suit you well if you are looking for a less restricted format for addiction treatment or simply need help with mental health.


    Therapy can be good step towards healing and self-discovery. If you need support without disrupting your routine, therapy offers a flexible solution for anyone wishing to enhance their mental well-being or work through personal issues in a supportive, confidential environment.

    Mental Health

    Are you having persistent feelings of being swamped, sad or have sudden surges of anger or intense emotional outbursts? These are warning signs of unresolved trauma mental health. A simple assesment by a mental health expert could provide valuable insights into your recovery.

    Finding the right rehab close to you is simple with WeDoRecover. Our network includes the finest rehab centers, ensuring personalised, quality care for your recovery needs. Let Gareth Carter and our empathetic team help guide you to a center that feels right for you, offering expert care and support. Start your healing today by choosing a rehab that's not just close to you, but also that truly cares about your loved ones recovery.

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