Opioid Full Agonist

We Do Recover

An Opioid Full Agonist is a medication that binds to and fully activates the opioid receptors in the brain, closely mimicking the effects of opioids. This action helps alleviate cravings and withdrawal symptoms in individuals managing opioid dependence. Common examples of these medications include methadone and buprenorphine, both of which are recognized by the WHO as essential medicines. Administered under medical supervision, these drugs are important in opioid agonist pharmacotherapy, aimed at specific treatment goals for opioid dependence.

Opioid drugs are categorized based on their interaction with the receptors. Full agonists like fentanyl, heroin, morphine, and oxycodone bind tightly to these receptors, producing strong effects. Partial agonists, such as buprenorphine and tramadol, also activate these receptors but to a lesser extent and their effectiveness diminishes at higher doses. Antagonists, on the other hand, block the opioid receptors, preventing other opioids from binding and thus blocking their effects. Mixed agonists/antagonists interact variably with different receptor types, acting as an agonist for some and an antagonist for others.

Methadone, a full agonist, activates opioid receptors slowly, avoiding the euphoria associated with other opioids, but still offers prolonged effects. Buprenorphine, a partial agonist, produces milder effects, which can be advantageous for those requiring less potent medication. Opioid receptors, involved in various bodily functions like pain and stress management, mood regulation, and behavior, contribute to the risk of substance use disorders and drug dependency. Treatment with opioid agonists, particularly in a comprehensive plan including counselling and therapy, provides stability and support during recovery, helping individuals regain control over their lives.

    Addiction and Mental Health

    Treatment Services

    Founded in 2008, WeDoRecover has evolved from an advisory service for addiction treatment into a comprehensive provider of care, following its 2019 merger with Changes Addiction Rehab in Johannesburg. Specializing in connecting patients to top-tier addiction treatment centers in the UK, South Africa, and Thailand, WeDoRecover supports individuals globally, including those from the United Arab Emirates and Europe. Accepting both South African medical aid and international health insurance, the organization facilitates access to high-quality treatment for substance and alcohol use disorders, offering individualized care that addresses the physical, mental, and social needs of patients.

    Our team, led by Gareth Carter, offers empathetic and professional support, guiding you through every step of the treatment process. Whether you're in South Africa or abroad, our acceptance of various insurance plans makes quality care accessible, providing a platform for lasting recovery and a healthier future.

    Inpatient Rehab

    Our rehab care is a good option if you are at risk of experiencing strong withdrawal symptoms when you try stop a substance. This rehab option would also be recommended if you have experienced recurrent relapses or if you have tried a less-intensive treatment without success.


    If you're committed to your sobriety but cannot take a break from your daily duties for an inpatient program. Outpatient rehab treatment might suit you well if you are looking for a less restricted format for addiction treatment or simply need help with mental health.


    Therapy can be good step towards healing and self-discovery. If you need support without disrupting your routine, therapy offers a flexible solution for anyone wishing to enhance their mental well-being or work through personal issues in a supportive, confidential environment.

    Mental Health

    Are you having persistent feelings of being swamped, sad or have sudden surges of anger or intense emotional outbursts? These are warning signs of unresolved trauma mental health. A simple assesment by a mental health expert could provide valuable insights into your recovery.

    Finding the right rehab close to you is simple with WeDoRecover. Our network includes the finest rehab centers, ensuring personalised, quality care for your recovery needs. Let Gareth Carter and our empathetic team help guide you to a center that feels right for you, offering expert care and support. Start your healing today by choosing a rehab that's not just close to you, but also that truly cares about your loved ones recovery.

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