Opioid-Induced Hyperalgesia

We Do Recover

Opioid-induced hyperalgesia (OIH) is a condition where prolonged use of opioid drugs, such as painkillers, leads to increased sensitivity to pain rather than reducing it. First observed in the 19th century, OIH gained scientific attention in the 20th century. It occurs when opioids, which normally alleviate pain by interacting with brain and spinal cord receptors, end up causing heightened pain sensitivity due to long-term use.

Patients undergoing opioid addiction treatment with full agonists like methadone or partial agonists like buprenorphine often experience significant hyperalgesia. Research indicates that methadone-maintained patients, for instance, show greater sensitivity to experimental pain than drug-free controls. This increased pain sensitivity can complicate the recovery process, particularly for those transitioning from short-acting opioids like heroin to long-acting substitution therapies.

Managing OIH involves considering alternative pain management strategies that minimize opioid use. This may include non-opioid medications, physical therapy, and psychological interventions. The phenomenon underscores the need for tailored pain management approaches in opioid addiction treatment and recovery. While OIH is specific to opioid use, it should not discourage individuals from seeking treatment, as the addiction recovery community is focused on improving pain management for those in recovery.

    Addiction and Mental Health

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    Founded in 2008, WeDoRecover has evolved from an advisory service for addiction treatment into a comprehensive provider of care, following its 2019 merger with Changes Addiction Rehab in Johannesburg. Specializing in connecting patients to top-tier addiction treatment centers in the UK, South Africa, and Thailand, WeDoRecover supports individuals globally, including those from the United Arab Emirates and Europe. Accepting both South African medical aid and international health insurance, the organization facilitates access to high-quality treatment for substance and alcohol use disorders, offering individualized care that addresses the physical, mental, and social needs of patients.

    Our team, led by Gareth Carter, offers empathetic and professional support, guiding you through every step of the treatment process. Whether you're in South Africa or abroad, our acceptance of various insurance plans makes quality care accessible, providing a platform for lasting recovery and a healthier future.

    Inpatient Rehab

    Our rehab care is a good option if you are at risk of experiencing strong withdrawal symptoms when you try stop a substance. This rehab option would also be recommended if you have experienced recurrent relapses or if you have tried a less-intensive treatment without success.


    If you're committed to your sobriety but cannot take a break from your daily duties for an inpatient program. Outpatient rehab treatment might suit you well if you are looking for a less restricted format for addiction treatment or simply need help with mental health.


    Therapy can be good step towards healing and self-discovery. If you need support without disrupting your routine, therapy offers a flexible solution for anyone wishing to enhance their mental well-being or work through personal issues in a supportive, confidential environment.

    Mental Health

    Are you having persistent feelings of being swamped, sad or have sudden surges of anger or intense emotional outbursts? These are warning signs of unresolved trauma mental health. A simple assesment by a mental health expert could provide valuable insights into your recovery.

    Finding the right rehab close to you is simple with WeDoRecover. Our network includes the finest rehab centers, ensuring personalised, quality care for your recovery needs. Let Gareth Carter and our empathetic team help guide you to a center that feels right for you, offering expert care and support. Start your healing today by choosing a rehab that's not just close to you, but also that truly cares about your loved ones recovery.

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