Opioid Partial Agonist

We Do Recover

Opioid partial agonists, vital in addiction treatment, work by simultaneously activating and blocking the brain’s opioid receptors, producing a limited physiological response. These drugs bind to opioid receptors like full agonists but with less intensity, offering relief from withdrawal symptoms without producing intense euphoria. Buprenorphine is a prominent example, aiding in gradually tapering off opioids while avoiding severe cravings, often leading to relapse. Available in various forms, such as dissolvable tablets or films, buprenorphine is an integral part of a comprehensive addiction treatment plan that includes counselling and therapy.

Opioid partial agonists, like buprenorphine and tramadol, differ from full agonists such as fentanyl, heroin, and morphine in their level of activation of opioid receptors. This results in a moderated opioid effect, beneficial for managing opioid dependence. The primary role of partial agonists in clinical settings is to alleviate cravings and withdrawal symptoms in the initial treatment stages, helping patients transition away from stronger opioids.

The ‘ceiling effect’ of partial agonists is a key advantage, wherein increasing the dose doesn’t proportionately increase the effect, thereby reducing overdose risk. This makes them a safer option, particularly in outpatient settings. Additionally, the reduced euphoria minimizes the risk of developing an addiction to the treatment medication itself, a significant concern in addiction therapy.

Effective in their role, opioid partial agonists should be part of a broader treatment plan, including counselling, behavioral therapy, and support groups. This holistic approach treats both the physical and psychological aspects of dependency, ensuring a comprehensive path to recovery.

    Addiction and Mental Health

    Treatment Services

    View More

    Founded in 2008, WeDoRecover has evolved from an advisory service for addiction treatment into a comprehensive provider of care, following its 2019 merger with Changes Addiction Rehab in Johannesburg. Specializing in connecting patients to top-tier addiction treatment centers in the UK, South Africa, and Thailand, WeDoRecover supports individuals globally, including those from the United Arab Emirates and Europe. Accepting both South African medical aid and international health insurance, the organization facilitates access to high-quality treatment for substance and alcohol use disorders, offering individualized care that addresses the physical, mental, and social needs of patients.

    Our team, led by Gareth Carter, offers empathetic and professional support, guiding you through every step of the treatment process. Whether you're in South Africa or abroad, our acceptance of various insurance plans makes quality care accessible, providing a platform for lasting recovery and a healthier future.

    Inpatient Rehab

    Our rehab care is a good option if you are at risk of experiencing strong withdrawal symptoms when you try stop a substance. This rehab option would also be recommended if you have experienced recurrent relapses or if you have tried a less-intensive treatment without success.


    If you're committed to your sobriety but cannot take a break from your daily duties for an inpatient program. Outpatient rehab treatment might suit you well if you are looking for a less restricted format for addiction treatment or simply need help with mental health.


    Therapy can be good step towards healing and self-discovery. If you need support without disrupting your routine, therapy offers a flexible solution for anyone wishing to enhance their mental well-being or work through personal issues in a supportive, confidential environment.

    Mental Health

    Are you having persistent feelings of being swamped, sad or have sudden surges of anger or intense emotional outbursts? These are warning signs of unresolved trauma mental health. A simple assesment by a mental health expert could provide valuable insights into your recovery.

    Finding the right rehab close to you is simple with WeDoRecover. Our network includes the finest rehab centers, ensuring personalised, quality care for your recovery needs. Let Gareth Carter and our empathetic team help guide you to a center that feels right for you, offering expert care and support. Start your healing today by choosing a rehab that's not just close to you, but also that truly cares about your loved ones recovery.

    Scroll to top