Partial Agonists

We Do Recover

Partial agonists are a type of drug that attach to and activate receptors in the body but not as completely as full agonists. They can act in two ways: they can activate receptors partially when there’s not enough of the natural substance the body usually produces for these receptors, or they can reduce overactivation of these receptors when there’s too much of the natural substance. If both a full agonist (which fully activates a receptor) and a partial agonist are present, the partial agonist can actually block some of the effects of the full agonist. Some common drugs that are partial agonists include buspirone, aripiprazole, buprenorphine, and THC. These drugs can have various effects, like THC’s psychoactive effects, which are due to its partial agonist action at certain receptors in the brain.

One commonly prescribed partial agonist is buprenorphine. This medication is often used to alleviate withdrawal symptoms and diminish cravings in individuals addicted to opioids. Buprenorphine attaches to the brain receptors, activating them to a lesser extent than opioids, allowing individuals to gradually wean off the drug without experiencing severe withdrawal symptoms.

Another partial agonist, known as methadone, is also used for opioid addiction treatment. Methadone works similarly by targeting the same receptors, preventing withdrawal symptoms and reducing cravings. However, it requires careful monitoring and administration within specialized clinics.

Partial agonists can be an important part of addiction treatment, as they can help stabilize individuals and make it easier for them to focus on their recovery. These medications are often used in conjunction with therapy and counselling to address the underlying causes and triggers of addiction.

The use of partial agonists in addiction treatment is not a recent development. Methadone, for example, has been utilized in the United States since the 1960s, while buprenorphine gained approval in the early 2000s. These medications have proven to be effective tools in combating addiction and supporting individuals on their path to recovery.

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    Founded in 2008, WeDoRecover has evolved from an advisory service for addiction treatment into a comprehensive provider of care, following its 2019 merger with Changes Addiction Rehab in Johannesburg. Specializing in connecting patients to top-tier addiction treatment centers in the UK, South Africa, and Thailand, WeDoRecover supports individuals globally, including those from the United Arab Emirates and Europe. Accepting both South African medical aid and international health insurance, the organization facilitates access to high-quality treatment for substance and alcohol use disorders, offering individualized care that addresses the physical, mental, and social needs of patients.



    Our team, led by Gareth Carter, offers empathetic and professional support, guiding you through every step of the treatment process. Whether you're in South Africa or abroad, our acceptance of various insurance plans makes quality care accessible, providing a platform for lasting recovery and a healthier future.


    Inpatient Rehab

    Our rehab care is a good option if you are at risk of experiencing strong withdrawal symptoms when you try stop a substance. This rehab option would also be recommended if you have experienced recurrent relapses or if you have tried a less-intensive treatment without success.

    Outpatient

    If you're committed to your sobriety but cannot take a break from your daily duties for an inpatient program. Outpatient rehab treatment might suit you well if you are looking for a less restricted format for addiction treatment or simply need help with mental health.

    Therapy

    Therapy can be good step towards healing and self-discovery. If you need support without disrupting your routine, therapy offers a flexible solution for anyone wishing to enhance their mental well-being or work through personal issues in a supportive, confidential environment.

    Mental Health

    Are you having persistent feelings of being swamped, sad or have sudden surges of anger or intense emotional outbursts? These are warning signs of unresolved trauma mental health. A simple assesment by a mental health expert could provide valuable insights into your recovery.


    Finding the right rehab close to you is simple with WeDoRecover. Our network includes the finest rehab centers, ensuring personalised, quality care for your recovery needs. Let Gareth Carter and our empathetic team help guide you to a center that feels right for you, offering expert care and support. Start your healing today by choosing a rehab that's not just close to you, but also that truly cares about your loved ones recovery.


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